Iatrogenic cushing syndrome
نویسندگان
چکیده
منابع مشابه
Iatrogenic Cushing\'s Syndrome Due to Cutaneous Corticosteroid Therapy
Summary A case of Cushing' s syndrome associated with application of topical clobetasol propionate (0.05%) is reported. Local application of clobetasol propionate is associated with adrenal suppression in normal subjects and on this basis, it has been recommended that less than 50 g per week be used. There have been sporadic case reports of cushing's syndrome associated with topical steroid bu...
متن کاملPreventing Cushing: Iatrogenic Cushing Syndrome due to Ritonavir-Fluticasone Interaction
Ritonavir is commonly used in low doses to boost plasma levels of protease inhibitors in patients with human immunodeficiency virus (HIV) infections. It is also a potent inhibitor of cytochrome P450. We present a 50-year-old African American male with past medical history of HIV on highly active antiretroviral therapy (HAART), which also included ritonavir and long standing asthma that has been...
متن کاملProgression of Kaposi sarcoma associated with iatrogenic Cushing syndrome in a person with HIV/AIDS.
This case report describes an exacerbation of AIDS-associated Kaposi sarcoma (KS) in the setting of iatrogenic Cushing syndrome caused by an interaction between ritonavir-boosted atazanavir and fluticasone. Discontinuation of fluticasone resulted in resolution of the cutaneous KS. Clinicians should be aware of this potential drug-drug interaction that can result in increased corticosteroid leve...
متن کاملIatrogenic Cushing Syndrome Secondary to Ritonavir-Epidural Triamcinolone Interaction: An Illustrative Case and Review
HIV positive patients on ritonavir-containing antiretroviral therapy (ART) can develop iatrogenic Cushing syndrome (IACS) and adrenal insufficiency as a result of drug-drug interactions with inhaled or intranasal glucocorticoid therapy. Reports related to epidural triamcinolone injections are relatively uncommon but increasingly reported. We describe a 48-year-old woman with immunologically and...
متن کاملIatrogenic Cushing syndrome and adrenal insufficiency during concomitant therapy with ritonavir and fluticasone
Ritonavir is a potent inhibitor of the cytochrome P450 enzyme CYP3A4 and is subject to multiple drug-drug interactions. This becomes especially important when the patient is also taking medications metabolized through CYP3A pathway as increased and potentially toxic drug levels may ensue. Herein we present one such interaction wherein a 57 year old gentleman with human immunodeficiency virus (H...
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ژورنال
عنوان ژورنال: Indian Pediatrics
سال: 2012
ISSN: 0019-6061,0974-7559
DOI: 10.1007/s13312-012-0147-9